Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence

Arrestin translocation and signaling have come to the fore of the G protein-coupled receptor molecular pharmacology field. Some receptor–arrestin interactions are relatively well understood and considered responsible for specific therapeutic or adverse outcomes. Coupling of arrestins with cannabinoi...

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Principais autores:	Mikkel Søes Ibsen, David B. Finlay, Monica Patel, Jonathan A. Javitch, Michelle Glass, Natasha Lillia Grimsey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-04-01
coleção:	Frontiers in Pharmacology
Assuntos:	cannabinoid receptor 1 (CB1) cannabinoid receptor 2 (CB2) G protein-coupled receptor (GPCR) arrestin cannabinoid signaling bias
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2019.00350/full
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