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Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors (DART) SWOG S1609: the desmoid tumors

Background Dual inhibition using anti-programmed death-1 (PD-1) and anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) checkpoint inhibitors has proven effective in many cancers. However, its efficacy in rare solid cancers remains unclear. Desmoid tumors are ultrarare soft-tissue tumors, traditionally t...

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Hlavní autoři: Howard Streicher, Elad Sharon, Razelle Kurzrock, Young Kwang Chae, Megan Othus, Sandip Patel, Christine McLeod, Charles Blanke, Benjamin Powers, Chung-Tsen Hsueh, Helen X Chen, Hye Sung Kim, Liam Il-Young Chung, Christopher W Ryan, Rangaswamy Govindarajan, Silvana Bucur
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2024-09-01
Edice:Journal for ImmunoTherapy of Cancer
On-line přístup:https://jitc.bmj.com/content/12/9/e009128.full
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