MAP3K Family Review and Correlations with Patient Survival Outcomes in Various Cancer Types

The mitogen-activated protein kinase (MAPK) pathways are ubiquitous in cellular signaling and are essential for proper biological functions. Disruptions in this signaling axis can lead to diseases such as the development of cancer. In this review, we discuss members of the MAP3K family and correlate...

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Principais autores:	Khoa Nguyen, Minh N. Tran, Andrew Rivera, Thomas Cheng, Gabrielle O. Windsor, Abraham B. Chabot, Jane E. Cavanaugh, Bridgette M. Collins-Burow, Sean B. Lee, David H. Drewry, Patrick T. Flaherty, Matthew E. Burow
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	IMR Press 2022-05-01
סדרה:	Frontiers in Bioscience-Landmark
נושאים:	map kinases mapk map3k understudied kinase dark kinome illuminating the druggable genome cancer
גישה מקוונת:	https://www.imrpress.com/journal/FBL/27/5/10.31083/j.fbl2705167
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