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Macrophage NPM1 drives anti-tumor immunity via the STAT3-CCRL2 axis

BackgroundAlthough nucleophosmin (NPM1) is a well-characterized oncogene in acute myeloid leukemia, much less is known about its role in solid tumor immunity. Here, we examined the function of NPM1 in regulating anti-tumor immunity within the tumor microenvironment.MethodsThe proportion and function...

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Bibliografiske detaljer
Principais autores: Lei Hong, Yue Yang, Yuwen Han, Nan Ouyang, Minxuan Sun, Rongchuan Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1748791/full
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