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Anergy into T regulatory cells: an integration of metabolic cues and epigenetic changes at the Foxp3 conserved non-coding sequence 2 [version 1; referees: 2 approved]

Peripheral immune self-tolerance relies on protective mechanisms to control autoreactive T cells that escape deletion in the thymus. Suppression of autoreactive lymphocytes is necessary to avoid autoimmunity and immune cell–mediated damage of healthy tissues. An intriguing relationship has emerged b...

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Principais autores: Milagros Silva Morales, Daniel Mueller
Formato: Artigo
Idioma:Inglês
Publicado em: F1000 Research Ltd 2018-12-01
coleção:F1000Research
Acesso em linha:https://f1000research.com/articles/7-1938/v1
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