IL-27 promotes cardiac fibroblast activation and aggravates cardiac remodeling post myocardial infarction

Excessive and chronic inflammation post myocardial infarction (MI) causes cardiac fibrosis and progressive ventricular remodeling, which leads to heart failure. We previously found high levels of IL-27 in the heart and serum until day 14 in murine cardiac ischemia‒reperfusion injury models. However,...

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Autori principali:	Xiaoxue Ma, Qingshu Meng, Shiyu Gong, Shanshan Shi, Xiaoting Liang, Fang Lin, Li Gong, Xuan Liu, Yinzhen Li, Mimi Li, Lu Wei, Wei Han, Leng Gao, Zhongmin Liu, Xiaohui Zhou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2023-06-01
Serie:	Heliyon
Soggetti:	IL-27 Fibroblast Myocardial infarction Inflammation Ventricular remodeling
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2405844023043074
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