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Reappraisal of oxidized HMGB1 as a mediator and biomarker

HMGB1 is a dual-function protein that acts as a chromatin-binding protein and as a danger-associated molecular pattern (DAMP) when released from activated immune cells or injured tissue. In much of the HMGB1 literature, immunomodulatory effects of extracellular HMGB1 are proposed to depend on its ox...

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Библиографические подробности
Главные авторы: Ross Pirnie, Kevin P Gillespie, Clementina Mesaros, Ian A Blair
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis Group 2022-12-01
Серии:Future Science OA
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Online-ссылка:https://www.future-science.com/doi/10.2144/fsoa-2022-0052
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