Structure–Activity Relationship Study Reveals the Molecular Basis for Specific Sensing of Hydrophobic Amino Acids by the <i>Campylobacter jejuni</i> Chemoreceptor Tlp3

Chemotaxis is an important virulence factor of the foodborne pathogen <i>Campylobacter jejuni</i>. Inactivation of chemoreceptor Tlp3 reduces the ability of <i>C. jejuni</i> to invade human and chicken cells and to colonise the jejunal mucosa of mice. Knowledge of the structure of the ligand-binding...

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Autors principals:	Mohammad F. Khan, Mayra A. Machuca, Mohammad M. Rahman, Cengiz Koç, Raymond S. Norton, Brian J. Smith, Anna Roujeinikova
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-05-01
Col·lecció:	Biomolecules
Matèries:	<i>Campylobacter jejuni</i> chemoreceptor methyl-accepting chemotaxis protein dCache high-throughput screening
Accés en línia:	https://www.mdpi.com/2218-273X/10/5/744
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