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Glycosylation signature of plasma IgA of critically ill COVID-19 patients

Thromboembolic complications are common in severe COVID-19 and are thought to result from excessive neutrophil-extracellular-trap (NET)-driven immunothrombosis. Glycosylation plays a vital role in the efficiency of immunoglobulin A (IgA) effector functions, with significant implications for NET form...

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Principais autores: Daniel P. Potaczek, Bianca D. M. van Tol, David Falck, Christina Krolczik, Kristina Zlatina, Wilhelm Bertrams, Jochen Wilhelm, Bernd Schmeck, Benjamin Seeliger, Sascha David, Chrysanthi Skevaki, Elisabeth Mack, Werner Seeger, Liliana Schaefer, Sebastian P. Galuska, Manfred Wuhrer, Małgorzata Wygrecka
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-10-01
Serier:Frontiers in Immunology
Fag:
ARDS
COVID-19
glycosylation
immunoglobulin A
NETosis
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1439248/full
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