Robust estimates of overall immune-repertoire diversity from high-throughput measurements on samples
Diversity of an organism’s B- and T-cell repertoires is clinically important, but difficult to estimate due to uncertainty in the number of clones in a sample, sampling bias and experimental noise. Here Kaplinsky and Arnaout present Recon, a method that reconstructs the distribution of the overall r...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2016-06-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/ncomms11881 |
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