Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors

ATP acts in the extracellular environment as an important signal, activating a family of receptors called purinergic receptors. In recent years, interest in the potential therapeutics of purinergic components, including agonists and antagonists of receptors, has increased. Currently, many observatio...

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Hlavní autoři:	Paulo Anastácio Furtado Pacheco, Daniel Tadeu Gomes Gonzaga, Natalia Lidmar von Ranke, Carlos Rangel Rodrigues, David Rodrigues da Rocha, Fernando de Carvalho da Silva, Vitor Francisco Ferreira, Robson Xavier Faria
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-01-01
Edice:	Molecules
Témata:	naphthoquinones sulfonamides heterocycles biomass ATP inflammation
On-line přístup:	https://www.mdpi.com/1420-3049/28/2/590
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