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Inter-domain communication mechanisms in an ABC importer: a molecular dynamics study of the MalFGK2E complex.

ATP-Binding Cassette transporters are ubiquitous membrane proteins that convert the energy from ATP-binding and hydrolysis into conformational changes of the transmembrane region to allow the translocation of substrates against their concentration gradient. Despite the large amount of structural and...

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Bibliographic Details
Main Authors: A Sofia F Oliveira, António M Baptista, Cláudio M Soares
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3150292?pdf=render
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