Role of Endocytosis Proteins in Gefitinib-Mediated EGFR Internalisation in Glioma Cells

EGFR (epidermal growth factor receptor), a member of the ErbB tyrosine kinase receptor family, is a clinical therapeutic target in numerous solid tumours. EGFR overexpression in glioblastoma (GBM) drives cell invasion and tumour progression. However, clinical trials were disappointing, and a molecul...

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Hlavní autoři:	Elisabete Cruz Da Silva, Laurence Choulier, Jessica Thevenard-Devy, Christophe Schneider, Philippe Carl, Philippe Rondé, Stéphane Dedieu, Maxime Lehmann
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-11-01
Edice:	Cells
Témata:	glioblastoma cell invasion membrane trafficking tyrosine kinase inhibitors
On-line přístup:	https://www.mdpi.com/2073-4409/10/11/3258
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