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Lactobacillus paracasei R3 protects against dextran sulfate sodium (DSS)-induced colitis in mice via regulating Th17/Treg cell balance

Abstract Inflammatory bowel diseases (IBD), mainly comprising ulcerative colitis (UC) and Crohn's Disease, are most often a polygenic disorder with contributions from the intestinal microbiome, defects in barrier function, and dysregulated host responses to microbial stimulation. Strategies that tar...

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Autori principali: Juan Huang, Ziyan Yang, Yanyun Li, Xingxing Chai, Yanfang Liang, Bihua Lin, Ziyu Ye, Shaobing Zhang, Zhengping Che, Hailiang Zhang, Xueying Zhang, Zhao Zhang, Tao Chen, Weiqing Yang, Jincheng Zeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2021-08-01
Serie:Journal of Translational Medicine
Soggetti:
Lactobacillus paracasei
Colitis
Dextran sulfate sodium
Treg
Th17
Whole genome sequencing
Accesso online:https://doi.org/10.1186/s12967-021-02943-x
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