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Asymmetric total synthesis of benzenoid cephalotane-type diterpenoids through a cascade C(sp2) & C(sp3)–H activation

Abstract Cephalotane diterpenoids, featuring unique and complicated carbon skeletons and remarkable antitumor activities from the Cephalotaxus genus, have been gaining increasing attention. Herein, we report the asymmetric and divergent total synthesis of benzenoid cephalotane-type diterpenoids cont...

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Principais autores: Xiangxin Li, Zhaoxu Lu, Shaocong Liu, Mengyao Sun, Shengfu Duan, Zhixiang Xie
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-05-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-025-59816-w
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