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Immunotherapy Targeting Myeloid-Derived Suppressor Cells (MDSCs) in Tumor Microenvironment

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that accumulate in tumor-bearing hosts to reduce T cells activity and promote tumor immune escape in the tumor microenvironment (TME). The immune system in the TME can be stimulated to elicit an anti-tu...

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Principais autores: Xidan Gao, Hongshu Sui, Shang Zhao, Xingmei Gao, Yanping Su, Peng Qu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-02-01
coleção:Frontiers in Immunology
Assuntos:
cancer
tumor immunotherapy
tumor microenvironment
myeloid-derived suppressor cells
inhibitory factors
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2020.585214/full
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