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Transcriptomic analysis of DENV-2-infected human dermal fibroblasts identified potential mechanisms that suppressed ZIKV replication during sequential coinfection

Abstract Dengue virus (DENV) and Zika virus (ZIKV) are closely related flaviviruses which are transmitted by the same species of mosquitoes. Due to overlapping geographic distributions and transmission vectors, cases of DENV-ZIKV coinfection have been reported. However, the impact of coinfection on...

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Principais autores: Chernkhwan Kaofai, Tuksin Jearanaiwitayakul, Khwankhao Saisingha, Jitra Limthongkul, Promsin Masrinoul, Sukathida Ubol
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-05-01
Series:Virology Journal
Assuntos:
Dengue virus
Zika virus
Coinfection
Human dermal fibroblasts
Transcriptomic profiling
Superinfection exclusion
Acceso en liña:https://doi.org/10.1186/s12985-025-02769-9
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