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Biased localization of actin binding proteins by actin filament conformation

The assembly of actin filaments into distinct cytoskeletal structures plays a critical role in cell physiology. Here, the authors use a combination of live cell imaging and in vitro single molecule binding measurements to show that tandem calponin homology domains (CH1–CH2) are sensitive to actin fi...

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Autori principali: Andrew R. Harris, Pamela Jreij, Brian Belardi, Aaron M. Joffe, Andreas R. Bausch, Daniel A. Fletcher
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2020-11-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-020-19768-9
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