Psoriatic microRNAs induce NK cell activation via an innate immune crosstalk abrogated by the Toll-like receptor 7/8 antagonist Enpatoran

Abstract Background MicroRNAs (miRNAs) are short regulatory RNAs that can be released in extracellular vesicles and, under pathological conditions such as autoimmunity, activate innate immune cells through Toll-like receptor (TLR) 7 and 8. This mechanism may sustain chronic inflammation. Psoriasis i...

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Bibliografiset tiedot

Päätekijät:	Carolina Gaudenzi, Irene Lo Cigno, Helena Stabile, Roberta Maggio, Francesca Bianchi, Gaia Giongrandi, Stefania Zini, Tiziana Schioppa, Laura Tiberio, Angela Ceribelli, Carlo Selmi, Marisa Gariglio, Angela Gismondi, Silvano Sozzani, Annalisa Del Prete, Flavia Bazzoni, Daniela Bosisio, Valentina Salvi
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2026-03-01
Sarja:	Journal of Translational Medicine
Linkit:	https://doi.org/10.1186/s12967-026-07909-5
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