MitoRS, a method for high throughput, sensitive, and accurate detection of mitochondrial DNA heteroplasmy

Abstract Background Mitochondrial dysfunction is linked to numerous pathological states, in particular related to metabolism, brain health and ageing. Nuclear encoded gene polymorphisms implicated in mitochondrial functions can be analyzed in the context of classical genome wide association studies....

ver descrição completa

Detalhes bibliográficos

Principais autores:	Julien Marquis, Gregory Lefebvre, Yiannis A. I. Kourmpetis, Mohamed Kassam, Frédéric Ronga, Umberto De Marchi, Andreas Wiederkehr, Patrick Descombes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-04-01
coleção:	BMC Genomics
Assuntos:	Next generation sequencing Mitochondria Mitochondrial DNA Heteroplasmy Rolling circle amplification Somatic mutation
Acesso em linha:	http://link.springer.com/article/10.1186/s12864-017-3695-5
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!