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Integrated cross-species translation and biophysical multi-scale modeling links molecular signatures and locomotory phenotypes in spaceflight-induced sarcopenia

Abstract Age-related skeletal muscle deterioration, referred to as sarcopenia, poses significant risks to astronaut health and mission success during spaceflight, yet its multisystem drivers remain poorly understood. While terrestrial sarcopenia manifests gradually through aging, spaceflight induces...

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Bibliographic Details
Main Authors: Brendan K. Ball, Hammad F. Khan, Jee Hyun Park, Krishna Jayant, Deva D. Chan, Douglas K. Brubaker
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2026-01-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-025-00557-x
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