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Identification of TonB-dependent siderophore receptor inhibitors against Flavobacterium columnare using a structure-based high-throughput virtual screening method

TonB-dependent siderophore receptors play a critical transport role for Flavobacterium columnare virulence formation and growth, and have become valuable targets for the development of novel antimicrobial agents. Traditional Chinese medicine has demonstrated notable efficacy in the treatment of fish...

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Autors principals: Minghao Li, Baipeng Chen, Ming Xu, Fulong Li, Yi Geng, Defang Chen, Ping Ouyang, Xiaoli Huang, Yongqiang Deng
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-05-01
Col·lecció:Frontiers in Microbiology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1392178/full
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