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Impact of IgG subclass on molecular properties of monoclonal antibodies

Immunoglobulin G-based monoclonal antibodies (mAbs) have become a dominant class of biotherapeutics in recent decades. Approved antibodies are mainly of the subclasses IgG1, IgG2, and IgG4, as well as their derivatives. Over the decades, the selection of IgG subclass has frequently been based on the...

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Autors principals: Yu Tang, Paul Cain, Victor Anguiano, James J. Shih, Qing Chai, Yiqing Feng
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2021-01-01
Col·lecció:mAbs
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Accés en línia:https://www.tandfonline.com/doi/10.1080/19420862.2021.1993768
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