Global Transcriptomics Uncovers Distinct Contributions From Splicing Regulatory Proteins to the Macrophage Innate Immune Response

Pathogen sensing via pattern recognition receptors triggers massive reprogramming of macrophage gene expression. While the signaling cascades and transcription factors that activate these responses are well-known, the role of post-transcriptional RNA processing in modulating innate immune gene expre...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Allison R. Wagner, Haley M. Scott, Kelsi O. West, Krystal J. Vail, Timothy C. Fitzsimons, Aja K. Coleman, Kaitlyn E. Carter, Robert O. Watson, Kristin L. Patrick
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2021-07-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	pre-mRNA splicing RNA binding protein inflammation hnRNP SR protein Salmonella Typhimurium
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.656885/full
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