Mechanistic Insights into the Metabolic Pathways Using High-Resolution Mass Spectrometry and Predictive Models in Pancreatic β-Cell Lines (β-TC-6)
Objectives: We have previously shown that inhibition of the mTORC1 nutrient-sensing complex by rapamycin and mTORC1/mTORC2 inhibition by either Torin-2 or RapaLink-1 have differential effects on the global untargeted metabolomics in in vivo and in vitro cell culture models. Methods: In this study, w...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2023-11-01
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| Schriftenreihe: | Biology and Life Sciences Forum |
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| Online-Zugang: | https://www.mdpi.com/2673-9976/29/1/16 |
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