Comparative study on the functions of LDHA and LDHC in triple-negative breast cancer

Abstract Background Lactate dehydrogenase (LDH) is a key enzyme in the aerobic glycolysis pathway (Warburg effect) of tumors. Triple-negative breast cancer (TNBC), a subtype of breast cancer, is characterized by elevated levels of the LDHA isoenzyme. However, related research is limited, and whether...

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Podrobná bibliografie

Hlavní autoři:	Lizhu Zeng, Chunlin Lv, Caiyun Deng, Siyu Yang, Xianglian Tian, Yuxia He, Qinglian Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2026-03-01
Edice:	Discover Oncology
Témata:	Triple-negative breast cancer (TNBC) LDHA LDHC PI3K/AKT/mTOR pathway Epithelial-mesenchymal transition (EMT)
On-line přístup:	https://doi.org/10.1007/s12672-026-04838-z
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