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Therapeutic Potential of Targeting the PERK Signaling Pathway in Ischemic Stroke

Many pathologic states can lead to the accumulation of unfolded/misfolded proteins in cells. This causes endoplasmic reticulum (ER) stress and triggers the unfolded protein response (UPR), which encompasses three main adaptive branches. One of these UPR branches is mediated by protein kinase RNA-lik...

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Bibliografische gegevens
Hoofdauteurs: Xinyuan Yu, Lihong Dang, Ran Zhang, Wei Yang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2024-03-01
Reeks:Pharmaceuticals
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Online toegang:https://www.mdpi.com/1424-8247/17/3/353
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