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Sacituzumab govitecan in triple-negative breast cancer: from bench to bedside, and back

Triple-negative breast cancer (TNBC) represents a major therapeutic challenge due to its heterogeneous and aggressive phenotype, and limited target-specific treatment options. The trophoblast cell surface antigen (Trop-2), a transmembrane glycoprotein overexpressed in various cancers, has emerged as...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Valentina Rossi, Alessandra Turati, Antonio Rosato, Debora Carpanese
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2024-08-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1447280/full
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