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Investigation of the proteolytic functions of an expanded cercarial elastase gene family in Schistosoma mansoni.

Cercarial elastase is the major invasive larval protease in Schistosoma mansoni, a parasitic blood fluke, and is essential for host skin invasion. Genome sequence analysis reveals a greatly expanded family of cercarial elastase gene isoforms in Schistosoma mansoni. This expansion appears to be uniqu...

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Principais autores: Jessica R Ingram, Salma B Rafi, A Alegra Eroy-Reveles, Manisha Ray, Laura Lambeth, Ivy Hsieh, Debbie Ruelas, K C Lim, Judy Sakanari, Charles S Craik, Matthew P Jacobson, James H McKerrow
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2012-01-01
Serier:PLoS Neglected Tropical Diseases
Online adgang:http://europepmc.org/articles/PMC3317910?pdf=render
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