Proton-coupled transport mechanism of the efflux pump NorA
Abstract Efflux pump antiporters confer drug resistance to bacteria by coupling proton import with the expulsion of antibiotics from the cytoplasm. Despite efforts there remains a lack of understanding as to how acid/base chemistry drives drug efflux. Here, we uncover the proton-coupling mechanism o...
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| Principais autores: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2024-05-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-024-48759-3 |
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