Leukocyte filtration and leukocyte modulation therapy during extracorporeal cardiopulmonary resuscitation in a porcine model of prolonged cardiac arrest

Abstract Extracorporeal cardiopulmonary resuscitation (ECPR) is emerging as a feasible and effective rescue strategy for prolonged cardiac arrest (CA). However, prolonged total body ischemia and reperfusion can cause microvascular occlusion that prevents organ reperfusion and recovery of function. O...

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Główni autorzy:	Jensyn J. VanZalen, Takahiro Nakashima, Annie Phillips, Joseph E. Hill, Angela J. Westover, Liandi Lou, Jinhui Liao, Joshua Mergos, Garrett Fogo, Thomas H. Sanderson, William C. Stacey, Mohamad Hakam Tiba, David H. Humes, Robert H. Bartlett, Alvaro Rojas-Peña, Robert W. Neumar
Format:	Artigo
Język:	Inglês
Wydane:	Nature Portfolio 2024-06-01
Seria:	Scientific Reports
Hasła przedmiotowe:	Extracorporeal cardiopulmonary resuscitation Cardiac arrest Inflammation Leukocyte modulation Neutrophil extracellular traps Animal models
Dostęp online:	https://doi.org/10.1038/s41598-024-63522-w
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