Assessing the performance of European-derived cardiometabolic polygenic risk scores in South-Asians and their interplay with family history

Abstract Background & aims We aimed to assess the performance of European-derived polygenic risk scores (PRSs) for common metabolic diseases such as coronary artery disease (CAD), obesity, and type 2 diabetes (T2D) in the South Asian (SAS) individuals in the UK Biobank. Additionally, we studied the...

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Päätekijät:	Emadeldin Hassanin, Carlo Maj, Hannah Klinkhammer, Peter Krawitz, Patrick May, Dheeraj Reddy Bobbili
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2023-07-01
Sarja:	BMC Medical Genomics
Aiheet:	Type 2 diabetes Family History South Asians Polygenic risk Coronary artery disease
Linkit:	https://doi.org/10.1186/s12920-023-01598-5
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