Calmodulin-dependent protein kinase II activation promotes kidney mesangial expansion in streptozotocin-induced diabetic mice

Calcium-calmodulin-dependent protein kinase II (CaMKII) is upregulated in diabetes mellitus (DM), leading to the overproduction of collagen in the myocardium. We hypothesized that CaMKII plays a role in the development of diabetic nephropathy (DN). Streptozotocin (STZ) injection into FVB wild-type m...

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Autors principals:	Alexei V. Mikhailov, Yixi Liu, Heng-Jie Cheng, Jen-Jar Lin, Che Ping Cheng
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-11-01
Col·lecció:	Heliyon
Matèries:	Diabetic nephropathy Streptozotocin Calmodulin-dependent protein kinase II KN-93 Mesangium WEKA Image J plugin
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2405844022029413
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