Expression of glucocorticoid receptor and HDACs in airway smooth muscle cells is associated with response to steroids in COPD
Abstract Background Steroid insensitivity in Chronic Obstructive Pulmonary Disease (COPD) presents a problem for controlling the chronic inflammation of the airways. The glucocorticoid receptor (GR) mediates the intracellular signaling of inhaled corticosteroids (ICS) by interacting with transcripti...
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2024-05-01
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| Серія: | Respiratory Research |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s12931-024-02769-3 |
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