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Effects of smoking on genome-wide DNA methylation profiles: A study of discordant and concordant monozygotic twin pairs

Background: Smoking-associated DNA methylation levels identified through epigenome-wide association studies (EWASs) are generally ascribed to smoking-reactive mechanisms, but the contribution of a shared genetic predisposition to smoking and DNA methylation levels is typically not accounted for. Met...

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Principais autores: Jenny van Dongen, Gonneke Willemsen, BIOS Consortium, Eco JC de Geus, Dorret I Boomsma, Michael C Neale
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2023-08-01
Serier:eLife
Fag:
epigenetics
DNA methylation
twin study
identical twins
discordant twins
Online adgang:https://elifesciences.org/articles/83286
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