Anti-Obesity Drug Orlistat Alleviates Western-Diet-Driven Colitis-Associated Colon Cancer via Inhibition of STAT3 and NF-κB-Mediated Signaling

Many researchers have argued that Western diet (WD)-induced obesity accelerates inflammation and that inflammation is a link between obesity and colorectal cancer (CRC). This study investigated the effect of WDs on the development and progression of colitis-associated colon cancer (CAC) and the effi...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Bo-Ram Jin, Hyo-Jung Kim, Seo-Ah Sim, Minho Lee, Hyo-Jin An
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2021-08-01
Цуврал:	Cells
Нөхцлүүд:	colitis-associated colon cancer (CAC) NF-κB STAT3 azoxymethane (AOM)/dextran sulfate sodium (DSS) model Western diet orlistat
Онлайн хандалт:	https://www.mdpi.com/2073-4409/10/8/2060
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!