Soluble factors released from fibroblast-like synoviocytes of JIA patients with future extended course can condition persistent JIA synovial fibroblasts for increased IL-6 production

Abstract Background Juvenile Idiopathic Arthritis (JIA) includes a subset of oligoarticular patients who later extend to a polyarticular course (extended-to-be, ETB), resulting in worse outcomes. Predictors of extension remain poorly defined. We investigated whether interleukin-6 (IL-6) and fibrobla...

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Principais autores:	Megan M. Simonds, Lina Al-Jaberi, Hermine I. Brunner, AnneMarie C. Brescia
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2026-03-01
סדרה:	Arthritis Research & Therapy
נושאים:	Juvenile Idiopathic Arthritis Fibroblast-like Synoviocytes Interleukin-6
גישה מקוונת:	https://doi.org/10.1186/s13075-026-03783-0
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