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A Rationale for the Activity of Bone Target Therapy and Tyrosine Kinase Inhibitor Combination in Giant Cell Tumor of Bone and Desmoplastic Fibroma: Translational Evidences

Giant cell tumor of bone (GCTB) and desmoplastic fibroma (DF) are bone sarcomas with intermediate malignant behavior and unpredictable prognosis. These locally aggressive neoplasms exhibit a predilection for the long bone or mandible of young adults, causing a severe bone resorption. In particular,...

Täydet tiedot

Tallennettuna:
Päätekijät: Alessandro De Vita, Silvia Vanni, Giacomo Miserocchi, Valentina Fausti, Federica Pieri, Chiara Spadazzi, Claudia Cocchi, Chiara Liverani, Chiara Calabrese, Roberto Casadei, Federica Recine, Lorena Gurrieri, Alberto Bongiovanni, Toni Ibrahim, Laura Mercatali
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2022-02-01
Sarja:Biomedicines
Aiheet:
bone sarcoma
giant cell tumor of bone
desmoplastic fibroma
primary culture
3D scaffold
gene expression profiling
Linkit:https://www.mdpi.com/2227-9059/10/2/372
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