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GLUL stabilizes N-Cadherin by antagonizing β-Catenin to inhibit the progresses of gastric cancer

Glutamate-ammonia ligase (GLUL, also known as glutamine synthetase) is a crucial enzyme that catalyzes ammonium and glutamate into glutamine in the ATP-dependent condensation. Although GLUL plays a critical role in multiple cancers, the expression and function of GLUL in gastric cancer remain unclea...

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Автори: Qiwei Jiang, Yong Li, Songwang Cai, Xingyuan Shi, Yang Yang, Zihao Xing, Zhenjie He, Shengte Wang, Yubin Su, Meiwan Chen, Zhesheng Chen, Zhi Shi
Формат: Artigo
Мова:Inglês
Опубліковано: Elsevier 2024-02-01
Серія:Acta Pharmaceutica Sinica B
Предмети:
Gastric cancer
GLUL
N-Cadherin
β-Catenin
Enzyme
Protein-protein interaction
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S2211383523004318
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