Radiotherapy‐resistant prostate cancer cells escape immune checkpoint blockade through the senescence‐related ataxia telangiectasia and Rad3‐related protein

Abstract Background The majority of patients with prostate cancer (PCa) exhibit intrinsic resistance to immune checkpoint blockade (ICB) following radiotherapy (RT). This resistance is generally attributed to the limited antigen presentation of heterogeneous cells within tumors. Here, we aimed to is...

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Detalhes bibliográficos

Principais autores:	Chenyi Shao, Yingyi Zhang, Hang Li, Jiajia Chen, Ting Huang, Jiaze Li, Simeng Wen, Sen Wang, Saijun Fan, Yu Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-03-01
coleção:	Cancer Communications
Assuntos:	ATR CD86 immune checkpoint senescence
Acesso em linha:	https://doi.org/10.1002/cac2.12636
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