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Acetylation of Response Regulator Protein MtrA in M. tuberculosis Regulates Its Repressor Activity

MtrA is an essential response regulator (RR) protein in M. tuberculosis, and its activity is modulated after phosphorylation from its sensor kinase MtrB. Interestingly, many regulatory effects of MtrA have been reported to be independent of its phosphorylation, thereby suggesting alternate mechanism...

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Uloženo v:
Hlavní autoři: Krishna Kumar Singh, P. J. Athira, Neerupma Bhardwaj, Devendra Pratap Singh, Uchenna Watson, Deepak Kumar Saini
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-01-01
Edice:Frontiers in Microbiology
Témata:
acetylation
phosphorylation
DNA binding protein
mycobacteria
response regulator
acetyl phosphate
On-line přístup:https://www.frontiersin.org/articles/10.3389/fmicb.2020.516315/full
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