The R2TP complex stabilises E7 to drive human papillomavirus-mediated pathogenesis in cellular models of cervical cancer

Abstract Human papillomaviruses (HPVs), particularly types 16 and 18, are major contributors to cervical cancer through the oncogenic activities of the E6 and E7 proteins. These viral proteins inactivate the tumour suppressors p53 and pRB, driving uncontrolled cellular proliferation. In this study,...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Mahaiwon Shadang, Aruna Arumugam, Dhiraj Kumar Singh, Pankaj Keshari, Sandeep Mathur, Venkateswaran K. Iyer, Seema Singhal, Shyam S. Chauhan, Qulsum Akhter, Riyaz Ahmad Mir
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2026-03-01
Sarja:	Virology Journal
Aiheet:	Human papillomavirus E7 Tumour virus PRB Cervical cancer Chaperones
Linkit:	https://doi.org/10.1186/s12985-026-03070-z
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!