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Carboxy-terminal domain of Cas differentially modulates c-Jun expression, DNA synthesis, and membrane ruffling induced by insulin, EGF, and IGF-1

p130 Crk-associated substrate (Cas) is an adaptor protein associating with many other signaling proteins and regulates a various biological processes including cell adhesion, migration, and growth factor stimulation. However, the exact functional role of Cas in growth factor signaling pathway was po...

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Principais autores: Sun-Ju Yi, Seong Yun Hwang, Myung-ju Oh, Kyunghwan Kim, Byung H. Jhun
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2018-03-01
Serier:Animal Cells and Systems
Fag:
Cas
microinjection
EGF
insulin
IGF-1
c-Jun expression
DNA synthesis
membrane ruffling
Online adgang:http://dx.doi.org/10.1080/19768354.2018.1447013
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