O-GlcNAcylation: a pro-survival response to acute stress in the cardiovascular and central nervous systems

Abstract O-GlcNAcylation is a unique monosaccharide modification that is ubiquitously present in numerous nucleoplasmic and mitochondrial proteins. The hexosamine biosynthesis pathway (HBP), which is a key branch of glycolysis, provides the unique sugar donor UDP-GlcNAc for the O-GlcNAc modification...

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Principais autores:	Qiu Xue, Shengtao Ji, Hui Xu, Shu Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-03-01
coleção:	European Journal of Medical Research
Assuntos:	O-GlcNAcylation Stress tolerance Cardioprotection Neuroprotection Hexosamine biosynthetic pathway
Acesso em linha:	https://doi.org/10.1186/s40001-024-01773-z
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