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Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System

Objective. To examine whether retinal electrophysiology is a useful surrogate marker of drug penetrance into the central nervous system (CNS). Materials and Methods. Brain and retinal electrophysiology were assessed with full-field visually evoked potentials and electroretinograms in conscious and a...

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Hlavní autoři: Jason Charng, Zheng He, Algis J. Vingrys, Rebecca L. Fish, Rachel Gurrell, Bang V. Bui, Christine T. Nguyen
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2016-01-01
Edice:Journal of Ophthalmology
On-line přístup:http://dx.doi.org/10.1155/2016/5801826
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