One-step grafting of temperature-and pH-sensitive (N-vinylcaprolactam-co-4-vinylpyridine) onto silicone rubber for drug delivery

A one-step method was implemented to graft N-vinylcaprolactam (NVCL) and 4-vinylpyridine (4VP) onto silicone rubber (SR) films using gamma radiation in order to endow the silicone surface with temperature- and pH-responsiveness, and give it the ability to host and release diclofenac in a controlled...

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Detalhes bibliográficos

Principais autores:	Victor H. Pino-Ramos, Carmen Alvarez-Lorenzo, Angel Concheiro, Emilio Bucio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2017-01-01
coleção:	Designed Monomers and Polymers
Assuntos:	Dually responsive silicone rubber drug-eluting device diclofenac sodium cytocompatibility bacteria adhesion
Acesso em linha:	http://dx.doi.org/10.1080/15685551.2016.1231033
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