Underlying pharmacological mechanisms of psilocin-induced broadband desynchronization and disconnection of EEG in rats

IntroductionPsilocybin is one of the most extensively studied psychedelic drugs with a broad therapeutic potential. Despite the fact that its psychoactivity is mainly attributed to the agonism at 5-HT2A receptors, it has high binding affinity also to 5-HT2C and 5-HT1A receptors and indirectly modula...

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Detalhes bibliográficos

Principais autores:	Filip Tylš, Čestmír Vejmola, Vlastimil Koudelka, Václava Piorecká, Lukáš Kadeřábek, Marcel Bochin, Tomáš Novák, Martin Kuchař, Zdeňka Bendová, Martin Brunovský, Jiří Horáček, Tomáš Pálení ček
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-06-01
coleção:	Frontiers in Neuroscience
Assuntos:	serotonergic psychedelics psilocybin/psilocin model of acute psychosis quantitative EEG power spectra phase-lagged coherence
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fnins.2023.1152578/full
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