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The Beneficial Effect of Mitochondrial Transfer Therapy in 5XFAD Mice via Liver–Serum–Brain Response

We recently reported the benefit of the IV transferring of active exogenous mitochondria in a short-term pharmacological AD (Alzheimer’s disease) model. We have now explored the efficacy of mitochondrial transfer in 5XFAD transgenic mice, aiming to explore the underlying mechanism by which the IV-in...

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Principais autores: Sahar Sweetat, Keren Nitzan, Nir Suissa, Yael Haimovich, Michal Lichtenstein, Samar Zabit, Sandrine Benhamron, Karameh Akarieh, Kumudesh Mishra, Dinorah Barasch, Ann Saada, Tamar Ziv, Or Kakhlon, Haya Lorberboum-Galski, Hanna Rosenmann
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-03-01
Serier:Cells
Fag:
mitochondria
Alzheimer’s disease
mitochondrial transfer
5XFAD
amyloid
cognition
Online adgang:https://www.mdpi.com/2073-4409/12/7/1006
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