In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions.
In the prevailing model of HIV-1 trans-infection, dendritic cells (DCs) capture and internalize intact virions and transfer these virions to interacting T cells at the virological synapse. Here, we show that HIV-1 virions transmitted in trans from in vitro derived DCs to T cells principally originat...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2007-01-01
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| Seria: | PLoS Pathogens |
| Dostęp online: | https://doi.org/10.1371/journal.ppat.0030004 |
| Etykiety: |
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