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Advances and challenges in CAR-T cell therapy for head and neck squamous cell carcinoma

Abstract Head and neck squamous cell carcinoma (HNSCC) remains among the most aggressive malignancies with limited treatment options, especially in recurrent and metastatic cases. Despite advances in surgery, radiotherapy, chemotherapy, and immune checkpoint inhibitors, survival rates remain subopti...

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Principais autores: Sahand Saeidpour Masouleh, Kamyar Nasiri, Ava Ostovar Ravari, Mona Saligheh Rad, Kiarash kiani, Ali Sharifi Sultani, Seyedeh Tabasom Nejati, Mohsen Nabi Afjadi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-05-01
Serier:Biomarker Research
Fag:
Head and neck squamous cell carcinoma
Chimeric antigen receptor T-cell therapy
Immunotherapy
CRISPR
Online adgang:https://doi.org/10.1186/s40364-025-00783-1
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